Figure 2: Heterozygotes grow stochastically in the presence of nystatin. | Nature Communications

Figure 2: Heterozygotes grow stochastically in the presence of nystatin.

From: Loss-of-heterozygosity facilitates passage through Haldane’s sieve for Saccharomyces cerevisiae undergoing adaptation

Figure 2

Homozygous (blue) and heterozygous (purple) mutant diploid lines were grown in YPD+2 μM nystatin. Stochastic growth was observed in all 20 BMN lines (shown here is a representative sample). (a) BMN1, which has a mutation in ERG7, (b–e) BMN3, 5, 9 and 13, which contain mutations in ERG6, (f–i) BMN21, 23, 28 and 32, which contain mutations in ERG3, and (j) BMN35, which has a mutation in ERG5. The same initial culture was placed into five replicate wells for each BMN line.

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