Table 2 Quantified HC phenotypes.

From: Retinoic acid signalling regulates the development of tonotopically patterned hair cells in the chicken cochlea

 

Control

RA

Citral

 

Proximal

Distal

Proximal

Distal

Proximal

Distal

Stereocilia number (mean±s.e.m.)

79.3±5.6

nBPs=8

nHCS=96

48.6±3.2

nBPs=8

nHCS=65

54.4±3.1

nBPs=6

nHCS=54

26.0±1.8

nBPs=6

nHCS=53

104.6±10.1

nBPs=8

nHCS=68

56.9±3.2

nBPs=8

nHCS=76

Hair bundle height (μm)

2.14±0.23

nBPs=8

nHCS=169

3.03±0.13

nBPs=8

nHCS=282

3.48±0.17

nBPs=9

nHCS=218

2.79±0.23

nBPs=9

nHCS=181

1.42±0.12

nBPs=6

nHCS=156

1.80±0.21

nBPs=6

nHCS=114

Luminal surface area (μm2)

28.4±2.44

nBPs=15

nHCS=242

11.17±0.85

nBPs=15

nHCS=228

14.82±1.48

nBPs=20

nHCS=359

9.15±0.72

nBPs=20

nHCS=322

33.07±3.37

nBPs=12

nHCS=189

13.74±0.94

nBPs=12

nHCS=197

  1. Quantitative analyses of the hair cell phenotypes that formed in proximal and distal regions of E6.5 BPs treated with control media or media supplemented with RA or citral. Values shown are mean±s.e.m.
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