Figure 8: siRNA against Itgb1 reduces overactivation of various signalling pathways in spontaneous liver tumour.

(a) Western blot analysis of tumour tissues treated by control siRNA. (b) Quantification of the western blot (a) (n=3–4, means±s.e.m., comparison by the Turkey post hoc test). (c) Immunohistochemical analysis of phosphorylated Stat3 expression in the liver tissues (arrows indicate positively stained nuclei). Scale bar, 100 μm. NTC, non-tumour control mice.