Figure 4: Hepatocyte Tlr4 promotes the development of hepatic steatosis and liver injury in mice. | Nature Communications

Figure 4: Hepatocyte Tlr4 promotes the development of hepatic steatosis and liver injury in mice.

From: Hepatocyte Toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance

Figure 4

(a) Liver weight in mice fed either chow (n=8) or HFD (n=10) for 12 weeks. (b) Liver triglyceride contents (n=8–9). (c) Liver cholesterol contents (n=8–9). (d) Relative hepatic mRNA levels of genes in HFD-fed mice (n=4–6). (e) Plasma ALT and AST levels (n=10) from HFD-fed Tlr4fl/fl and Tlr4LKO mice. *P<0.05, compared between Tlr4fl/fl and Tlr4LKO mice on the same diet; #P<0.05, compared between different diets for mice of the same genotype (Student’s t-test). All data are presented as means±s.e.m.

Back to article page