Figure 3: Synthesis of four diastereosiomers of 4ea.

When a chiral propargylic alcohol was used, we got four diastereosiomers of 4ea easily using either (R,R)-N-Pinap or (R,S)-N-Pinap as the ligand with this protocol. equiv, equivalent.

When a chiral propargylic alcohol was used, we got four diastereosiomers of 4ea easily using either (R,R)-N-Pinap or (R,S)-N-Pinap as the ligand with this protocol. equiv, equivalent.