Figure 5: Imaging target engagement over time.
From: In vivo imaging of specific drug–target binding at subcellular resolution
(a) Anisotropy and corresponding fluorescence images of AZD2281–BODIPY FL at four representative time points during drug loading and after washing. (b) Similar experiment as in (a) but in the presence of fivefold higher concentration of unlabelled AZD2281 (competition). Scale bars, 20 μm.
