Figure 2: Identification of differentially expressed pseudogenes among established tumour subtypes. | Nature Communications

Figure 2: Identification of differentially expressed pseudogenes among established tumour subtypes.

From: The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes

Figure 2

(a) Numbers of significantly differentially expressed pseudogenes in multiple cancer types. For each cancer type, the whole bar represents the number of expressed pseudogenes (mean RPKM ≥0.3) in the analysis; the black part represents the number of expressed pseudogenes with a detected significance for differential expression among tumour subtypes (t-test or single-factor analysis of variance, corrected P<0.05) and the pie chart shows the sample numbers and percentages in each cancer type. (b) The box plot for the expression pattern of ATP8A2P1 in 837 BRCA samples based on PAM50 subtypes: luminal A (n=417), luminal B (n=191), basal-like (n=139), Her2-enriched (n=67) and normal-like (n=23). The boxes show the median±1 quartile, with whiskers extending to the most extreme data point within 1.5 interquartile range from the box boundaries.

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