Figure 8: Snail-dependent control of a Notch1-Dll4 regulatory cascade.
From: A Snail1/Notch1 signalling axis controls embryonic vascular development

Schematic outlining the ability of VEGF or bFGF to upregulate Dll4 expression and Notch signalling while simultaneously modulating Dll4 expression levels by co-inducing Snail1, resulting in Dll4 transcriptional repression.