Figure 6: Cluster plots of noteworthy SNPs. | Nature Communications

Figure 6: Cluster plots of noteworthy SNPs.

From: 2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy

Figure 6

Cluster plots are shown for rs4458204 (CCL20), rs1367610 (TGFBR2), rs2569254 (IL12B) and rs13422767 (IFIH1) for the BCAC samples that passed quality control in the parent COGS study18. The SNP genotypes have been assigned based on cluster formation in scatter plots of normalized allele intensities X and Y. Each circle represents one individual’s genotype. Blue and red clouds indicate homozygote genotypes for the SNP (AA/aa), green heterozygote (Aa) and black undetermined. Three distinct, tight clusters exhibited by all four representative SNPs indicate good discrimination of the three genotypes.

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