Figure 6: A diagrammatic model of ROS1 function in stomatal development. | Nature Communications

Figure 6: A diagrammatic model of ROS1 function in stomatal development.

From: Overproduction of stomatal lineage cells in Arabidopsis mutants defective in active DNA demethylation

Figure 6

(a) A model for ROS1 function in stomatal development. ROS1 negatively regulates the entry into the stomatal lineage through EPF2. The bHLH protein SPCH is necessary for establishing the stomatal lineage. The bHLH protein MUTE is required for the termination of meristemoid asymmetric division and for the promotion of the GMC cell-state transition. (b) ROS1 removes DNA methylation from the EPF2 promoter to enable expression of the EPF2 gene, and EPF2 peptides are secreted outside of the meristemoid mother cell (MMC) to be received by the ERECTA receptor in the cell membranes of neighbour cells, stomatal lineage ground cell (SLGC). (c) ROS1 and RdDM antagonistically regulate the DNA methylation status of the EPF2 promoter.

Back to article page