Table 1 Distribtion of CNVs across samples and estimated ancestry.

From: The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism

Continental ancestry

Case

Control

Total

Europe

 Number of samples

4,602

4,722

9,324

 *CNV burden (Kb)

63.3

54.5

 

Africa

 Number of samples

312

4,169

4,481

 *CNV burden (Kb)

70.4

48.0

 

America

 Number of samples

485

276

761

 CNV burden (Kb)

59.1

58.4

 

Asia

 Number of samples

201

350

551

 CNV burden (Kb)

56.1

54.1

 

Other

 Number of samples

27

127

154

 CNV burden (Kb)

51.5

49.4

 

All Ethnicities

 Number of samples

5,627

9,644

15,271

 *CNV burden (Kb)

63.0

51.7

 
  1. CNV=copy-number variation. The table shows the distribution of cases, controls and CNV coverage across estimated continental ancestry. For groups of cases and controls across estimated ancestries, the table lists the numbers of subjects that passed quality control and their group-wise CNV burden, defined as the average span of CNVs in Kb for each group.
  2. *Statistically significant (P≤0.01 by PLINK permutation test) differences in CNV burden are marked with an asterix(*).
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