Figure 10: LSD1 Tg mice are more sensitive to cold exposure.
From: LSD1 promotes oxidative metabolism of white adipose tissue
(a) Haematoxylin and eosin (H&E) staining, (b) western blot analysis of LSD1 and Ucp1 expression in mice exposed to cold for 0, 5, or 10 days. β-Tubulin was used as a loading control. (c) H&E staining, (d) western blot analysis of LSD1 and Ucp1, and (e) relative transcript levels of indicated genes of epWAT of Ctrl and Tg mice treated with vehicle or CL316,243. β-Tubulin was used as a loading control. Scale bars, 100 μm. (a–e): n=10; s.d.represents+s.e.m. Experiment (e) was independently repeated at least three times in triplicate. Statistical analysis was performed using two-tailed Student’s t-test. *P<0.05 and **P<0.01.
