Table 1 Pro-inflammatory phenotypes in wt and nfkb1−/− mice.
From: Chronic inflammation induces telomere dysfunction and accelerates ageing in mice
Phenotype | nfkb1 −/− (12 weeks) | nfkb1 −/− (36 weeks) | wt (12 weeks) | wt (36 weeks) | wt (104 weeks) | wt (132 weeks) |
|---|---|---|---|---|---|---|
Enlarged spleen* | 3/5 | 6/6 | 0/5 | 0/5 | 1/7 | 4/5 |
High systemic IL-6† | 0/5 | 5/5 | 0/4 | 2/5 | n.d. | 5/5 |
Liver: immune cell infiltration‡ | 1/5 | 5/5 | 0/5 | 0/5 | n.d. | 2/3 |
