Figure 3: Pharmocokinetic and tissue distribution studies of NCPs.

Tissue distributions of 1P (a) and 2P (c) z at time points of 5 min, 1, 3, 8, 24 and 48 h after i.v. injection of corresponding nanoparticles. Data are expressed as means±s.d. (n=3). Observed and fitted time-dependent Pt concentrations in plasma following 1P (b) and 2P (d) administration.