Figure 6: In vivo fluorescence imaging.

(a) Time-dependent fluorescence images of CT26 tumour-bearing mouse showing increasing tumour contrast due to the accumulation of Ce6-1P inside the tumour. (b) Digital camera image of the same mouse showing the tumour position. (c) Measurements of the fluorescence intensity of the tumour region (circular regions of interest shown in (a)). (d–g) Confocal fluorescence images of CT26 tumour cells. Channels are: DAPI nuclear stain (blue), apoptosis by TUNEL assays (green) and Chlorin e6 from the particles (red). Scale bars, 20 μm.