Figure 3: HOP2-MND1 enables RAD51 DNA strand exchange in the absence of divalent metal ions.
From: HOP2-MND1 modulates RAD51 binding to nucleotides and DNA

(a) Effect of mHOP2-MND1 (0.1 μM) on D-loop formation by hRAD51 (1 μM) with ssDNA (#186, 3 μM) and pUC19 scDNA (50 μM) in the presence of ATP at the indicated concentrations. D-loop formation was analysed by electrophoresis in a 1% agarose gel. (b) Data from (a) are shown as a graph. The experiments were repeated at least three times.