Figure 8: The eight conformations of BetP and BetP-G153D determined by X-ray crystallography to date (green): | Nature Communications

Figure 8: The eight conformations of BetP and BetP-G153D determined by X-ray crystallography to date (green):

From: Substrate-bound outward-open state of the betaine transporter BetP provides insights into Na+ coupling

Figure 8

substrate-free outward-open bound to sodium (Ce2Na) (PDB entry 4DOJ); substrate-bound outward-open (CeS) (PDB entry 4LLH, reported here); substrate-bound closed (CcS) (PDB entry 4AIN); substrate-bound inward-occluded (CiocS) (PDB entry 2WIT); substrate-bound inward-open (CiS) (PDB entries 4DOJ/3P03/4AIN/4LLH); substrate-free inward-open (Ci) (PDB entry 4AMR); substrate-free closed (Cc) (PDB entry 4AIN); and substrate-free outward-occluded (Ceoc) (PDB entry 4DOJ).

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