Figure 4: Thermogenesis of Wps/Wps mice at thermoneutrality and after HFD feeding.
From: The stem cell factor/Kit signalling pathway regulates mitochondrial function and energy expenditure
(a–c) Six-week-old Wt and Wps/Wps mice were housed at 30 °C for 1 week, and then were subjected for metabolic cage study at 30 °C for another 10 days. Data from the last 5 days were analysed and plotted (n=7–8). (a) Heat production adjusted to body weight using ANCOVA analysis, (b) RER and (c) locomotor activity. (d) Growth curve of 2-month-old mice after HFD feeding. (e) Body weight, lean mass, fat mass and fat percentage of mice after 12 weeks of HFD feeding (n=7). (f) Food intake, (g) locomotor activity, (h) heat production and (i) RER of HFD mice determined by metabolic cage study at room temperature (n=6–8). Data are shown as mean±s.e.m. *P<0.05 by two-tailed Student’s t-test.
