Figure 5: Acute toxicity of rDc1a in two cockroach families.

(a) Dose–response curve for lethal effects of rDc1a determined 24 h after injection into German cockroaches (B. germanica; family Blattellidae, closed circles). Data were fitted according to Equation 5 in Methods and represent mean±s.e.m. of three independent experiments. (b) Comparison of the KD₅₀ (open columns) and LD₅₀ (grey columns) doses at 24 h following injection of rDc1a in L. cuprina, M. domestica and B. germanica. Note: doses up to 5 nmol g⁻¹ failed to produce any signs of knockdown or lethality up to 72 h post injection in American cockroaches (Periplaneta americana; family Blattidae). Data represent mean±s.e.m. of three independent experiments.