Figure 1: Germline CTR9 mutations in familial Wilms tumour.
From: Germline mutations in the PAF1 complex gene CTR9 predispose to Wilms tumour
(a) Pedigrees of three Wilms tumour families with germline CTR9 mutations. The age at diagnosis and mutation are shown under the relevant individuals. (b) Sequencing chromatograms showing mutations in blood and tumour DNA and corresponding wild-type sequence from a control.
