Table 1 Wilms tumour families included in study.
From: Germline mutations in the PAF1 complex gene CTR9 predispose to Wilms tumour
Family ID | Relationship of relatives affected with Wilms tumour | Number of WT cases analyzed | Method of analysis |
|---|---|---|---|
FAM0072 | Two siblings | 1 | CTR9 Sanger sequencing |
FAM0091 | Two siblings | 1 | CTR9 Sanger sequencing |
FAM0123 | Two siblings | 2 | CTR9 Sanger sequencing |
FAM0349 | Two half first cousins once removed (parent's half first cousin) | 2 | Exome sequencing |
FAM0477 | Parent–child and possible history of more distantly affected relatives | 2 | CTR9 Sanger sequencing |
FAM0480 | Two siblings | 1 | CTR9 Sanger sequencing |
FAM0481 | Three first cousins | 2 | CTR9 Sanger sequencing |
FAM0484 | Two first cousins. Mothers are sisters and fathers are brothers | 1 | CTR9 Sanger sequencing |
FAM0485 | Two first cousins and one first cousin once removed (first cousin of obligate carrier parents) | 1 | CTR9 Sanger sequencing |
FAM0486 | Parent–child. Parent has affected half-sibling and first cousin | 1 | CTR9 Sanger sequencing |
FAM0487 | Uncle–child | 1 | CTR9 Sanger sequencing |
FAM0488 | Two half siblings | 2 | Exome sequencing |
FAM0489 | Two first cousins | 2 | CTR9 Sanger sequencing |
FAM0491 | Two first cousins | 1 | CTR9 Sanger sequencing |
FAM0492 | Parent–child | 1 | CTR9 Sanger sequencing |
FAM0493 | Two siblings | 2 | Exome sequencing |
FAM0498 | Parent–children (two children) | 2 | Exome sequencing |
FAM0499 | Uncle–child (via unaffected obligate carrier father) | 2 | CTR9 Sanger sequencing |
FAM0500 | Two first cousins | 1 | CTR9 Sanger sequencing |
FAM0501 | Two individuals are second cousins (one set of grandparents are siblings) and third cousins (one set of grandparents are first cousins) | 2 | CTR9 Sanger sequencing |
FAM0504 | Parent–child | 2 | CTR9 Sanger sequencing |
FAM0507 | Two half second cousins (grandparents are half siblings) | 2 | Exome sequencing |
FAM0508 | Parent–child | 1 | CTR9 Sanger sequencing |
FAM0509 | Two first cousins once removed (parent's first cousin) | 2 | CTR9 Sanger sequencing |
FAM0510 | Parent–child | 2 | CTR9 Sanger sequencing |
FAM0678 | Two siblings | 2 | CTR9 Sanger sequencing |
FAM0689 | Uncle–child (via unaffected obligate carrier mother) | 1 | CTR9 Sanger sequencing |
FAM2006 | Parent–children (two children) | 2 | CTR9 Sanger sequencing |
FAM2084 | Two second cousins | 1 | CTR9 Sanger sequencing |
FAM2097 | Two second cousins | 1 | CTR9 Sanger sequencing |
FAM3679 | Two siblings | 2 | CTR9 Sanger sequencing |
FAM3727 | Two siblings | 2 | Exome sequencing |
FAM5673 | Parent–child | 2 | CTR9 Sanger sequencing |
FAM5737 | Two second cousins | 1 | CTR9 Sanger sequencing |
FAM5804 | Parent–child | 2 | CTR9 Sanger sequencing |
