Figure 3: Mechanism of sulfa-Michael reaction. | Nature Communications

Figure 3: Mechanism of sulfa-Michael reaction.

From: Metal-templated chiral Brønsted base organocatalysis

Figure 3

Proposed ternary complex for the reaction 1a+2a→(R)-3a catalysed by Λ-IrBB1. It is noteworthy that the R-configuration of the sulfa-Michael addition products render a mechanism unlikely in which instead the α,β-unsaturated N-acyl pyrazole hydrogen bonds with the aminopyrazole ligand.

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