Table 2 Diversity within the six clonal complexes.

From: Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline

 

CC1

CC10

CC17

CC19

CC23

CC26

Strain name

BG-NI-011

DK-NI-008

COH1

RBH11

CCH210801006

Bangui-IP-105

Genome size*

2,078 (25)

2,080 (34)

2,065 (1)

2,180 (34)

2,055 (17)

2,054 (45)

No. of isolates

39

18

79

39

36

6

Interrogated regions†

914 kb

1,069 kb

1,860 kb

1,427 kb

980 kb

1,582 kb

Polymorphic positions

1,244

971

3,922

2,016

1,329

263

Recombination‡

987 kb

pil1, pil2, cps, R5, alp, srr

914 kb

pil1, pil2, cps, R5, alp, srr

68 kb

cps, R5

532 kb

cps, R5, pil2, srr, alp

875 kb

pil1, pil2, cps, R5, alp, srr

398 kb

Tn916/CRISPR, R5, alp

Depth§

174±23

126±7

129±16

97±21

169±16

74±34

Mutation rate||

0.64

—

0.56

0.93

0.75

—

  1. *Total contig size in kb, in parenthesis, the number of contigs.
  2. †Cumulative size in kb of regions not predicted to have recombined.
  3. ‡Cumulative size in kb of the recombined regions and the exchanged antigenic loci.
  4. §Expressed as the average number of single-nucleotide polymorphism (SNP) per Mb from the root to the tips of the tree for strains isolated after 2005.
  5. ||As estimated by dividing the depth of each lineage by its age predicted by the BEAST analysis, in SNPs per Mb per year (Fig. 1b–e).
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