Figure 5: Second-generation autocatalytic thiol–ene reaction.
From: Physical autocatalysis driven by a bond-forming thiol–ene reaction
The biphasic reaction of 4 and 5 produces 6. As 6 forms micelles above 5 mM, it was expected to catalyse the reaction, and hence the reaction was predicted to be autocatalytic. The use of a maleimide as the Michael acceptor allows the reaction to proceed under conditions more relevant to model protocells.
