Figure 3: Histological analysis of symptomatic mice.
From: Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis
Representative GFAP immunostaining of normal CMVrtTA and triple transgenic TRE-Omomyc;CMVrtTA;GFAP-V12Ha-Ras brains. Left panels show that astrocytic density is reduced in Omomyc-expressing mice. Center panels focus on residual GFAP-positive regions. Right panels show higher magnification of astrocytes and active microglia.
