Table 1 Three-stage study design of ovarian cancer GWAS in Chinese women.
No. of SNPs | Genotyping method | Source of population | Controls | Cases | |||
---|---|---|---|---|---|---|---|
N | Age (mean±s.d.) | N | Age (mean±s.d.) | ||||
Stage I | 900,015 | Illumina HumanOmniZhongHua-8 BeadChip | Northern* | 425 | 55.40±9.49 | 429 | 54.80±10.37 |
Southeasthern† | 747 | 52.86±10.81 | 615 | 54.10±10.43 | |||
Stage I total | 1,172 | 52.86±10.81 | 1,044 | 54.39±10.40 | |||
Stage II | 51‡ | Sequenom MassArray iPlex | Southeasthern† | 899 | 54.75±10.97 | 552 | 53.33±10.18 |
Southern§ | 900 | 51.87±13.38 | 408 | 50.70±12.49 | |||
Stage II total | 1,799 | 53.31±12.32 | 960 | 52.21±11.29 | |||
Stage III | 51‡ | Sequenom MassArray iPlex /Taqman | Northern|| | 1,004 | 52.50±11.44 | 492 | 53.69±11.79 |