Table 1 A comparison of SNP-typing systems.

From: A robust SNP barcode for typing Mycobacterium tuberculosis complex strains

SNP set and reference

Lineage classified (Number of sublineages classified)

No. of RD lineages covered

 

1

2

3

4

5

6

7

M. bovis

Total

 

This study

62 SNPs

Yes (8*)

Yes (6*)

Yes (5*)

Yes (36*)

Yes (0)

Yes (0)

Yes (0)

Yes (0)

7 (55)

19

Homolka et al.17

71 SNPs

Yes (1)

Yes (0)

Yes (0)

Yes (7§)

Yes (2||)

Yes (0)

No (−)

Yes (0)

6 (10)

NA

Comas et al.16

93 SNPs

Yes (1)

Yes (2)

Yes (0)

Yes (5#)

Yes (0)

Yes (0)

No (−)

Yes (0)

6 (7)

9**

Filliol et al.21

45 SNPs

No (−)

No (−)

No (−)

No (−)

No (−)

No (−)

No (−)

No (−)

6 (−)

NA

  1. NA, not applicable; RD, regions of difference; SNP, single-nucleotide polymorphism.
  2. *See Supplementary Data 1 for a complete description of lineages and sublineages.
  3. RD239, 105, 207, 181, 150, 142, 750, 182, 183, 193, 122, 726, 219, 761, 115, 174, 724, 711, 702; 239.
  4. Lineage 1.2.1.
  5. §Lineages 4.6.2.2, 4.1.2.1, 4.3, 4.4.1.1, 4.2.2.1, 4.2.1 and an ambiguous ‘Ghana’.
  6. ||West Africanum Ia and Ib.
  7. Lineages 2.1 and 2.2.
  8. #Lineages 4.6.2.2, 4.6.1, 4.1.1, 4.1.2.1 and 4.3.
  9. **RD105, 207, 750, 726, 724, 182, 711, 702 and 7.