Figure 2: The ability to block stress is not innate to all retroviruses. | Nature Communications

Figure 2: The ability to block stress is not innate to all retroviruses.

From: eEF2 and Ras-GAP SH3 domain-binding protein (G3BP1) modulate stress granule assembly during HIV-1 infection

Figure 2

(a) Phylogenetic tree of major retrovirus families used in this study (env gene). (b) HeLa cells were transfected or infected with HIV-2, SIV, EIAV, FIV, MLV or RSV and 48 h later were exposed to PatA. Cells were stained for gp41(SIV), p30(MLV), CA(FIV/RSV), G3BP1 and eIF3b, as indicated. Squares represent regions of interest. Scale bar, 30 μm. (c) NIH3T3 cells were transfected with MLV DNA (top) or Cos-7 cells were transfected with SIV DNA (bottom) and at 48 h exposed to PatA. Cells were stained for gp41(SIV), G3BP1, p30 (MLV) and UPF-1 as indicated. Scale bar, 30 μm.

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