Figure 2: Comparative analysis of WarpedLMM and a LMM for 58 phenotypes in the mouse data set.
From: Warped linear mixed models for the genetic analysis of transformed phenotypes
(a) Heritability estimates using a LMM on the untransformed phenotype versus the heritability estimates obtained by WarpedLMM. Empirical error bars were obtained from ten bootstrap replicates, using 90% of the data in each replicate. Significant differences are coloured in red (paired t-test, α=0.05). (b) Out-of-sample prediction accuracy assessed by the squared correlation coefficient r2, considering either a LMM on the untransformed data or a WarpedLMM. Prediction accuracies were assessed from ten random train-test splits. Phenotypes with significant deviations in prediction accuracy of the LMM and the WarpedLMM are highlighted in red (paired t-test, P-value≤0.05).
