Figure 3: Manhattan plots comparing a standard LMM to a WarpedLMM in a GWAS of two metabolic traits in the NFBC1966 study.
From: Warped linear mixed models for the genetic analysis of transformed phenotypes
(a) The GWAS results for C-reactive protein, and (b) the GWAS results for low-density lipoprotein. Red circles denote significant associations (α<5 × 10−8, marked on the plots with a dashed line). The two rightmost panels show an enlarged view of interesting regions in chromosomes 1 and 19, with black arrows highlighting loci that were identified only when using WarpedLMM.
