Figure 4: Crystal structure of prepore of LUK.
From: Molecular basis of transmembrane beta-barrel formation of staphylococcal pore-forming toxins
(a) Overall structure, top view (left) and side view (right). LukF and LukS are shown in red and cyan, respectively. (b) Stereo representation of 2Fo-Fc electron density map of the β-barrel contoured at 1.2 σ. Cα trace of the whole β-barrel structure of γ-HL is also shown. Orange: LukF, magenta: Hlg2. (c) Close-up view of the MPD-binding site. The bound MPD is shown as sticks. The Fo-Fc map (contoured at 1.5 σ) around the MPD is also shown.
