Figure 6: Global coordination roles of the Fur regulatory network in E. coli. | Nature Communications

Figure 6: Global coordination roles of the Fur regulatory network in E. coli.

From: Deciphering Fur transcriptional regulatory network highlights its complex role beyond iron metabolism in Escherichia coli

Figure 6

The Fur regulatory network is involved in many cellular functions required in addition to iron acquisition and utilization. Fur directly regulates genes associated with (a) iron metabolism, (b) DNA synthesis, (c) redirection of metabolism towards fermentative pathways and (d) biofilm formation for searching nutrients in response to iron availability. These networks are linked through the coordination role that Fur plays. Underlined characters indicate novel Fur regulon revealed in this study.

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