Figure 1: Chemical structures and cartoon representations.
From: Quantification of plasma HIV RNA using chemically engineered peptide nucleic acids
(a) aegPNA showing two nucleobases (B=A, T, G or C). (b) aegPNA–RNA duplex. (c) Cyclopentane-modified PNA. The partial structure may be extended in either direction with additional aegPNA or cyclopentane PNA residues. (d) General strategy by which biotins are attached to the C-terminal of a PNA to create a multivalent scaffold with biotins.
