Figure 1: Phylogenetic analysis of the largest subunit of RNAP in bacteria, euryarchaeota, crenarchaeota and eukaryotes.
From: The X-ray crystal structure of the euryarchaeal RNA polymerase in an open-clamp configuration
Maximum-likelihood phylogenetic tree made with the largest subunit of RNAP (β′ of bacterial RNAP, Rpo1′+Rpo1′′ of archaeal RNAP, and Rpb1 of eukaryotic RNAP II) rooted with bacterial sequences. Bootstrap support based on 500 replicates is shown at each node. Scale bar represents the average number of substitutions per residues. The position of common ancestor of archaeal–eukaryal RNAP is indicated in red. An order of Thermococcales including Pfu and Tko is highlighted.
