Figure 6: Model of clamp-conformation control through the stalk.
From: The X-ray crystal structure of the euryarchaeal RNA polymerase in an open-clamp configuration
(a) A nascent RNA, depicted as a dashed line, may stabilize the closed conformation of the clamp in the transcription elongation complex by the interaction with the stalk. (b) Binding of TFE/TFIIEα, shown as a grey ellipse, on the clamp and stalk may stabilize the open conformation of the clamp and stalk in the PIC.
