Figure 2: Immune characterization of croaker.
From: The draft genome of the large yellow croaker reveals well-developed innate immunity

(a) Proteins encoded by immune-relevant genes in croaker that are present in similar (green circles), higher (red circles) or lower (green circles with dashed outlines) numbers compared with other teleosts, and genes that are absent (grey circles with dashed outlines) in croaker. CIITA=major histocompatibility complex class II transactivator; GILT=gamma-interferon-inducible lysosomal thiol reductase; IFN=interferon; IL=interleukin; IRF=interferon regulatory factor; MHC=major histocompatibility complex; TNF=tumour necrosis factor; TLR=toll-like receptor. (b) Number of genes involved in the cellular component of the MHC class I protein complex (GO:0042612, blue bar) and the MHC class II protein complex (GO:0042613, red bar) in different teleosts. The exact numbers are shown on the top of each bar. The gene numbers in croaker that are significantly lower than those in stickleback are indicated by a single asterisk (P-value=0.08 for GO:0042613) or a double asterisk (P-value=0.0022 for GO:0042612) according to a proportion test.