Figure 2: AUF1 lowers the levels of target mRNA subsets.
From: PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity
(a) Relative overexpression of each AUF1 isoform, as assessed by RT-qPCR analysis; data are the means+s.d. from three independent experiments. (b) Cumulative distribution analysis in abundance of AUF1 PAR-CLIP target mRNAs after AUF1 overexpression. The red lines are almost exactly superimposed on the orange lines. (c) Cumulative distribution analysis of 3,105 AUF1 target mRNAs binned by target site number or T-to-C frequency. Significance in graphs in b,c was determined using the KS (Kolmogorov–Smirnov) test.
