Table 1 Number of in vivo experiments for each purpose

From: Graphene-based carbon-layered electrode array technology for neural imaging and optogenetic applications

Implant description

In vivo vascular imaging

Impedance spectroscopy

Baseline signal recordings

Electrical evoked potentials

Optogenetic experiments

Rat CLEAR device (chronic)

3

4

4

4

—

Rat Pt micro-ECoG device (chronic)

3

3

3

3

—

Mouse CLEAR device (terminal)

3

—

3

—

3

Mouse Pt micro-ECoG device (terminal)

2

—

2

—

2

  1. CLEAR, Carbon Layered Electrode Array; ECoG, electrocorticography.
  2. Table 1 describes the number of devices that were implanted during this study and the experiments they were used for. Multiple rats were implanted bilaterally, one device on each brain hemisphere, to serve as better within animal comparisons and to reduce total animals numbers used. Three rats were implanted bilaterally with one CLEAR micro-ECoG device and one platinum micro-ECoG device and one rat was implanted with a single CLEAR device. All rats were chronic studies. Five mice were implanted during terminal procedures. Three animals had CLEAR and platinum micro-ECoG devices implanted, and two had only the CLEAR device.
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