Table 1 Biological categories most often enriched in GWAS of the 100 most abundant OTUs.

From: Genome-wide association study of Arabidopsis thaliana leaf microbial community

Kingdom

Biological category

Number of OTUs

Rank

P -value

Fungi

Defense response

21

1

1 × 10−5

Fungi

Signal transduction

12

2

1 × 10−5

Fungi

Protein serine/threonine kinase activity

9

3

2 × 10−5

Bacteria

Defense response

9

1

1 × 10−5

Bacteria

Kinase activity

8

2

1 × 10−5

Bacteria

Casparian strip

7

3

0.00015

Bacteria

Cell wall modification

7

3

0.00015

Bacteria

Cell–cell junction assembly

7

3

0.00015

Bacteria

Plasma membrane part

7

3

0.00015

  1. GWAS, genome-wide association studies; OTU, operational taxonomic unit.
  2. Storey's procedure24 was used to correct for multiple testing (FDR≤10%). Only the top three enriched GO-terms are shown, unless there are ties among results. The probability of observing the same category across analyses was determined through 100,000 permutations (Methods).
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