Figure 4: De novo proteins compared with native ones. | Nature Communications

Figure 4: De novo proteins compared with native ones.

From: Protein design with a comprehensive statistical energy function and boosted by experimental selection for foldability

Figure 4

(a) Sequence and structure of Dv_1ubq compared with those of 1ubq. The distribution of identical residues is indicated. (b) Tertiary inter-residue contacts of Dv_1ubq compared with those of 1ubq. The upper triangle of the contact map shows contacts that are the same (that is, formed by the same two types of residues) in the two proteins. The lower triangle shows the remaining contacts. (c) Results of CD in induced denaturing of designed Dv_1ubq compared with native ubiquitin. (d,e) Same as in a,b, but for comparisons between D_1cy5_M2 and 1cy5.

Back to article page