Figure 5: ECC genomes encode an atypical CbpA. | Nature Communications

Figure 5: ECC genomes encode an atypical CbpA.

From: Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster

Figure 5

Canonical CbpA of TIGR4 compared with those in ECC genomes, and the inferred donor, S. agalactiae C beta antigen. Sequence most likely deriving from S. pneumoniae (grey) and S. agalactiae (white). Domains relevant to polymeric Ig receptor (pIgR) or IgA-binding are highlighted. The IgA-binding domain of S. agalactiae beta antigen is duplicated, and domain 2 has been divided into portions (a, b, c) for purposes of illustrating the likely origins of fragments that share amino-acid sequence identity in ECC variants.

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