Figure 5: Application of regiodivergent S–M cross-coupling products of heterocyclic allylic boronate 4. | Nature Communications

Figure 5: Application of regiodivergent S–M cross-coupling products of heterocyclic allylic boronate 4.

From: Synthesis of chiral heterocycles by ligand-controlled regiodivergent and enantiospecific Suzuki Miyaura cross-coupling

Figure 5

(a) Formal synthesis of (+)-anabasine, a tobacco component and agonist of the nicotinic acetylcholine receptor. (b) Formal synthesis of (+)-paroxetine, a synthetic antidepressant drug of the selective serotonin reuptake inhibitor class. a Product of a gram-scale reaction (with 1.4 g of (S)-4).

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