Figure 2: Architecture of the regulatory domain of citrin and aralar. | Nature Communications

Figure 2: Architecture of the regulatory domain of citrin and aralar.

From: Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers

Figure 2

(a) calcium-bound N- and C-terminal domain of citrin, and (b) calcium-bound and (c) calcium-free state of the N-terminal domain of aralar. Two views of the domains are shown in cartoon representation, related by a 90-degree rotation. Protomer A is coloured according to the scheme in Fig. 1a, whereas protomer B is coloured in light grey. Bound calcium ions are shown as green spheres. Protomers A and B of the calcium-free state structure shown here correspond to chains B and A, respectively.

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