Table 2 Subsequent memory (‘DM’)-related group activity after ROI-based alignment.

From: Laminar activity in the hippocampus and entorhinal cortex related to novelty and episodic encoding

Cluster size

Cluster P uncorr

Alpha (simulated)

Peak T

Peak location

Template x, y, z {mm}

Side

Group activity for 1.5 mm smoothing

21

0.007

<0.10

4.60

pyramidal CA1 (body)

31.1, 22.1,21.1

R

33

0.001

<0.02

4.58

EC & sub (head)

−14.6, 41.2, −26.0

L

16

0.017

<0.25

4.31

CA1/presub.(head)

15.1, 38.1,23.4

R

17

0.014

<0.20

4.20

CA2/3-DG (posterior body)

23.9, 14.8,12.7

R

Group activity for 2.4 mm smoothing

96

0.001

<0.01

5.94

CA1/presub. (head)

15.1, 38.1, −23.4

R

72

0.003

<0.01

5.51

EC

−13.8, 41.6, −25.3

L

25

0.053

<0.20

4.90

CA2/3-DG (posterior body)

25.5, 13.7,13.1

R

44

0.014

<0.05

4.49

pyramidal CA1 (body)

31.1, 22.5, −22.2

R

37

0.022

<0.10

4.31

Sub/CA1 (body)

22.3, 23.5,21.9

R

57

0.006

<0.02

4.05

EC

13.5, 34.5, −26.9

R

  1. DG, dentate gyrus; EC, entorhinal cortex; R, right; ROI, region of interest L, left.
  2. Functional data were smoothed with two different kernels to allow for higher specificity and higher sensitivity, respectively. Hippocampal and entorhinal subregions showing group-level activation (at Pvoxel level<0.005; k1.5 mm≥15 voxels and k2.4 mm≥25 voxels, N=19) for the DM contrast (difference due to memory: remembered>forgotten). Alphas were simulated with 3dClustSim (AFNI). Note that clusters that would not survive correction at low smoothing (highlighted in italics; for example, pyramidal layers in CA1) become significant with higher smoothing.