Figure 6: Beclin 1/Mcl-1 axis contributes to the progression of melanoma. | Nature Communications

Figure 6: Beclin 1/Mcl-1 axis contributes to the progression of melanoma.

From: Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner

Figure 6

(a) Beclin 1 and Mcl-1 levels in lysates derived from either tumour-adjacent normal (N) or malignant (M) tissues of five melanoma patients. (b) Immunohistochemical analysis of Beclin 1 and Mcl-1 levels in patient samples of benign nevi (n=7), primary melanoma (Prim Mela, n=28) or metastatic melanoma (Meta Mela, n=8). The bars represent the highest and lowest quartiles. (c) Representative images of immunohistochemical analysis (original magnification, × 200) Scale bar, 40 μm.

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