Table 1 Summary of exome sequencing results of tumour-control pairs from 102 ICC patients.
From: Mutational landscape of intrahepatic cholangiocarcinoma
Total | Median | Min | Max | Mean | |
|---|---|---|---|---|---|
Tumour/normal pair sequenced | 102 | ||||
Tumour sequenced (Gb) | 1,234 | 11 | 8 | 20 | 12 |
Normal sequenced (Gb) | 1,147 | 10 | 8 | 20 | 11 |
Tumour coverage | 81 | 44 | 118 | 80 | |
Normal coverage | 69 | 44 | 141 | 76 | |
%Tumour (≥15x) | 92% | 86% | 94% | 92% | |
%Normal (≥15x) | 92% | 86% | 93% | 92% | |
Somatic mutations in 102 patients | 8,380 | 63 | 16 | 373 | 82 |
Somatic mutation (/Mb) | 1.9 | 0.5 | 11.0 | 2.4 | |
Non-synonymous mutations | 5,941 | 44 | 8 | 275 | 58 |
Synonymous mutations | 2,439 | 19 | 5 | 98 | 24 |
Indels | 494 | 4 | 0 | 29 | 5 |
Splice sites alterations | 161 | 1 | 0 | 12 | 2 |
Genes with protein-coding changes | 3,637 | 30 | 0 | 249 | 46 |
