Figure 5: GRO-Seq distribution around protein-coding TSSs with divergent pri-miRNAs supporting the hypothesis that divergent transcription might play an additional role in the cell by generating mature miRNAs.

All identified precursor miRNAs are transcribed by the pri-miRNA region that exhibits a clear divergent transcription profile, since it fully overlaps with the GRO-Seq signal, which dissipates 2 kb upstream of coding TSSs.