Table 3 Karyotypes of primary lung fibroblasts.

From: Spartan deficiency causes genomic instability and progeroid phenotypes

Lung fibroblast genotype ( n)

Mitotic cells inspected

% Aneuploid figures

Karyotypes with the indicated chromosome number

   

37

38

39

40

41

42

43

Sprtn+/+ (2)

50

12

0

3

1

44

1

1

0

SprtnH/H (2)

50

36

1

5

2

32

6

2

2

  1. Karyotyping was performed with lung fibroblasts isolated from two mice per genotype (#45 and #46 for Sprtn+/+, #84 and #87 for SprtnH/H) at passage 5. Twenty-five mitotic figures were inspected for each sample.
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