Table 1 The percentage of larvae that showed lower serotonin signals in SE0PG neurons.

From: Serotonergic neurons respond to nutrients and regulate the timing of steroid hormone biosynthesis in Drosophila

GFP

Serotonin

96 hAH

120 hAH

−

−

30 (n=9)

17.9 (n=5)

+

−

10 (n=3)

82.1 (n=23)

+

+

60 (n=18)

0 (n=0)

 

%

100

100

  1. GFP, green fluorescent protein; hAH, hours after hatching; MARCM, mosaic analysis with a repressible cell marker; PG, prothoracic gland; rpr, reaper.
  2. The ‘GFP[–] and serotonin[−]’ group indicates that SE0PG neurons were lost by rpr. The ‘GFP[+] and serotonin[−]’ group indicates that SE0PG neurons were present but the serotonin signal decreased. The ‘GFP[+] and serotonin[+]’ group indicates that SE0PG neurons and the serotonin signal were detected on the PG. When the MARCM clone-induced larvae were dissected at 96 hAH (the wandering stage), 40% of these animals showed decreased level of serotonin in SE0PG neurons. In contrast, when the larvae delayed for pupariation were dissected at 120 hAH, all animals decreased serotonin signals in SE0PG neurons. Thus, the inhibition of SE0PG neurons leads to decreased level of serotonin, which correlates with the delayed timing of pupariation.
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