Figure 6: Trafficking of LTi-like ILC3s to the mLN after H. polygyrus infection requires CCR7.

(a) Total numbers of ILC2s and ILC3s per mLN in control versus infected mice, 7 and 14 dpi (n=12, 10, 5, 9, 11 and 3). (b) Detection of Ki-67 expression among LTi-like ILC3s, NKp46⁺ ILC3s and ILC2s in mLN from control and infected C57BL/6 mice at 7 dpi; data representative of three mice per cell type from two independent experiments. (c) Percentage of LTi-like ILC3s, NKp46⁺ ILC3s and ILC2s in the mLN that express Ki-67 in control and infected C57BL/6 mice at 7 dpi (n=3 and 5). (d) Total numbers of ILC1s, ILC2s and ILC3s per mLN from infected WT and CCR7^−/− mice at 7 dpi (n=6 and 5). (e) Total numbers of LTi-like and NKp46⁺ ILC3s per mLN from infected WT and CCR7^−/− mice at 7 dpi (n=6 and 5). (f) Expression of Ki-67 by WT and CCR7^−/− LTi-like ILC3s in the mLN at 7 dpi, representative of six mice from two independent experiments. (g) Percentage of LTi-like and NKp46⁺ ILC3s expressing Ki-67 in the mLN of C57BL/6 WT and CCR7^−/− mice at 7 dpi (n=6 and 7). *P<0.05, **P<0.01, ***P<0.001 and ****P<0.0001 (Mann–Whitney non-parametric, two-tailed test). Data are pooled or representative of two independent experiments, bars represent the median values in all graphs.